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RJG-2051

Product Specifications

CAS Number

2851993-77-4

Target

Reductase

Related Pathways

Metabolism|||Endocrinology/Hormones

Bioactivity

RJG-2051 is a selective covalent inhibitor of aldo-keto reductase family 1 member C3 (AKR1C3), with an IC50 value of 13 nM. It interferes with the metabolism of substrates such as androgens, estrogens, and prostaglandins through AKR1C3. RJG-2051 holds potential for cancer research.

Smiles

O=C(C1=CC=C(C=C1)S(=O)(=O)N2N=C(N=C2)C3CCCCC3)N4CCN(C=5C=CC=CC5OC)CC4

Molecular Formula

C26H31N5O4S

Molecular Weight

509.62

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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