STING-IN-14
Product Specifications
CAS Number
3070953-78-2
Target
STING
Related Pathways
Immunology/Inflammation
Bioactivity
STING-IN-14 is a STING inhibitor with an IC50 of 0.6 nM. It effectively suppresses the activation of the IRF pathway in THP1-DualTM cells. This compound is applicable in research related to autoimmune diseases.
Smiles
O=C1[C@]2(N(C3=C4C(N(N=C4)C5=C(F)C=C(F)C=C5)=NC=N3)C[C@](C2)(OC6=CC(C=7C=8C(=NN(C8)CCN9C(C(=O)NC[C@@H](C(NCC%10=CC=CC=C%10)=O)N1)COCC9)C=CC7)=CC=C6)[H])[H]
Molecular Formula
C46H43F2N11O5
Molecular Weight
867.901
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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