Pyrazole N-Desmethyl sildenafil
Product Specifications
CAS Number
139755-95-6
Target
Parasite|||PDE
Related Pathways
Microbiology/Virology|||Metabolism
Bioactivity
Pyrazole N-Desmethyl sildenafil (Compound 10) is an analogue of Sildenafil. At a concentration of 100 µM, it inhibits the activity of the Trypanosoma brucei phosphodiesterase TbrPDEB1 by 16%.
Smiles
CCCc1[nH]nc2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1
Molecular Formula
C21H28N6O4S
Molecular Weight
460.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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037155 200 µL
ITK, NT (ITK, EMT, LYK, Tyrosine-protein kinase ITK/TSK, Interleukin-2-inducible T-cell kinase, Kinase EMT, T-cell-specific kinase, Tyrosine-protein kinase Lyk)
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