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VEGFR-2-IN-59

Product Specifications

Target

VEGFR

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors

Bioactivity

VEGFR-2-IN-59 (Compound 3h) is an inhibitor of VEGFR2 with an IC50 of 3.73 µM. It exhibits cytotoxicity in cancer cell lines A549, HT-29, A375, MCF7, and NHDF, with IC50 values of 20.91, 19.70, 9.63, 17.43, and 20.71 ?M, respectively. VEGFR-2-IN-59 also inhibits tubular structure formation and demonstrates anti-angiogenic properties.

Molecular Formula

C19H20N6O4

Molecular Weight

396.4

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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