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FXR agonist 11

Product Specifications

CAS Number

2768502-17-4

Target

FXR

Related Pathways

Metabolism

Bioactivity

FXR agonist11 (Compound 14) is an FXR activator with an EC50 of 1.2 ?M and a maximal effect of 73.7%. It significantly increases GSH levels in the liver and is used to study drug-induced liver injury.

Smiles

O=C(O)C=1C=CC=C(C1)NC(=O)COC2=CC=C3C(=C2)NC(=O)CC3

Molecular Formula

C18H16N2O5

Molecular Weight

340.33

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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