Protoporphyrin IX disodium
Product Specifications
CAS Number
50865-01-5
Target
Endogenous Metabolite
Related Pathways
Metabolism
Bioactivity
Protoporphyrin IX disodium, as a radiation sensitizer, enhances the production of ROS and induces DNA damage even under hypoxic conditions. It also acts as a photosensitizer, undergoing direct degradation through photobleaching upon light exposure. This compound accumulates in rat tumor cells following administration of 5-aminolevulinic acid (5-ALA) . When activated with a peak wavelength of 405 nm, Protoporphyrin IX disodium selectively improves basal cell carcinoma. It shows promise in pharmacological research of sonodynamic and photodynamic therapy for cancers such as bladder cancer and nodular basal cell carcinoma.
Smiles
O=C(CCC1=C(C)C2=NC1=CC3=C(CCC([O-])=O)C(C)=C(N3)C=C(C(C=C)=C4C)N=C4C=C(C(C=C)=C5C)NC5=C2)[O-].[Na+].[Na+]
Molecular Formula
C34H32N4Na2O4
Molecular Weight
606.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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