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Protoporphyrin IX disodium

Product Specifications

CAS Number

50865-01-5

Target

Endogenous Metabolite

Related Pathways

Metabolism

Bioactivity

Protoporphyrin IX disodium, as a radiation sensitizer, enhances the production of ROS and induces DNA damage even under hypoxic conditions. It also acts as a photosensitizer, undergoing direct degradation through photobleaching upon light exposure. This compound accumulates in rat tumor cells following administration of 5-aminolevulinic acid (5-ALA) . When activated with a peak wavelength of 405 nm, Protoporphyrin IX disodium selectively improves basal cell carcinoma. It shows promise in pharmacological research of sonodynamic and photodynamic therapy for cancers such as bladder cancer and nodular basal cell carcinoma.

Smiles

O=C(CCC1=C(C)C2=NC1=CC3=C(CCC([O-])=O)C(C)=C(N3)C=C(C(C=C)=C4C)N=C4C=C(C(C=C)=C5C)NC5=C2)[O-].[Na+].[Na+]

Molecular Formula

C34H32N4Na2O4

Molecular Weight

606.62

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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