PROTAC 20S proteasome subunit ?5 degrader 2
Product Specifications
Target
PROTACs|||Proteasome
Related Pathways
Ubiquitination|||Proteases/Proteasome|||PROTAC
Bioactivity
PROTAC 20S proteasome subunit ?5 degrader 2 is a PROTAC degrader targeting the 20S proteasome subunit ?5 (20Sproteasomesubunit ?5), with a DC50 of 0.16 ?M. It inhibits the proliferation of FaDu cancer cells, showcasing an IC50 of 0.23 ?M. Additionally, PROTAC20Sproteasomesubunit ?5 degrader 2 demonstrates antitumor activity in a mouse model.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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