EG01377 2HCl
Product Specifications
CAS Number
2749438-61-5
Target
Complement System
Related Pathways
Immunology/Inflammation
Purity
0.9956
Bioactivity
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 ?M and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.EG01377 exhibits anti-angiogenic, antimigratory and antitumor activities.
Smiles
N=C(N)NCCC[C@@H](C(O)=O)NC(C(SC=C1)=C1NS(=O)(C2=C3C(CCO3)=CC(C4=CC=C(C=C4)CN)=C2)=O)=O.Cl.Cl
Molecular Formula
C26H32Cl2N6O6S2
Molecular Weight
659.6
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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