Monoclonal Anti-HE4 (Capture orDetectionAb)

WAP four-disulfide core domain protein 2 - also known as Human Epididymis Protein (HE4) - is a protein that in humans is encoded by the WFDC2 gene.HE4 is a tumor marker of ovarian cancer, with 80% sensitivity at a cut-off of 150 pmol/L. This gene encodes a protein that is a member of the WFDC domain family. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.

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