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Recombinant human PDCD5 (E36G) protein

PDCD5 (Programmed cell death 5) encodes a protein expressed in tumor cells during apoptosis independent of the apoptosis-inducing stimuli. Prior to apoptosis induction, this gene product is distributed in both the nucleus and cytoplasm. The conformation of PDCD5 protein is a stable helical core consisting of a triple-helix bundle and two dissociated terminal regions. This is an important novel protein that regulates both apoptotic and non-apoptotic programmed cell death. Recombinant PDCD5 was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Programmed cell death 5, TFAR19, Programmed cell death 5, PDCD5, Programmed cell death 5 Programmed cell death protein 5, TF-1 cell apoptosis-related protein 19, TFAR19 novel apoptosis-related.

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

14 kDa (125aa) confirmed by MALDI-TOF

Additionnal Information

PDCD5 (E36G), Programmed cell death 5, TFAR19, Programmed cell death 5, PDCD5, Programmed cell death 5 Programmed cell death protein 5, TF-1 cell apoptosis-related protein 19, TFAR19 novel apoptosis-related., PDC0802-10 µg, PDC0802-20 µg, PDC0802-50 µg, PDC0802-100 µg, PDC0802-250 µg, PDC0802-500 µg, PDC0802-1 mg, PDC0802-10, PDC0802-20, PDC0802-50, PDC0802-100, PDC0802-250, PDC0802-500, PDC0802-1

References & Citations

Chen Y., et al. (2001) . FEBS Lett. 509 (2) :191-6.; ; Wang., et al. (2007) . Apoptosis. 12 (8) :1433-41.; ; Liu D., et al. (2005) . Biochem J. 392, 47-54.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Scientific Category

Cancer

NCBI Accession Number

NP_004699

Uniprot Accession Number

O14737

Species

Human

AA Sequence

MADEELEALR RQRLAELQAK HGDPGDAAQQ EAKHRGAEMR NSILAQVLDQ SARARLSNLA LVKPEKTKAV ENYLIQMARY GQLSEKVSEQ GLIEILKKVS QQTEKTTTVK LNRRKVMDSD EDDDY

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