Recombinant human Granzyme H protein
GZMH, as known as granzyme H isoform 1, is a member of the granzyme family of serine proteases found specifically in the granules of cytotoxic Tlymphocytes (CTL) and natural killer (NK) cells. The more abundant expression of this protein than granzyme B in NK cells suggests that granzyme H may complement the pro-apoptotic function of granzyme B in this cell type. Recombinant human GZMH, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Granzyme H isoform 1, GZMH, CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
26.2 kDa (234aa)
Additionnal Information
References & Citations
Ronnberg E., et al. (2014) Int. Arch. Allergy Immunol. 165:68-74.; ; Tahbaz-Lahafi B., et al. (2014) Iran J Cancer Prev 7:48-52.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Apoptosis
NCBI Accession Number
NP_219491
Uniprot Accession Number
P20718
Species
Human
N Terminal Sequence
Glu19
AA Sequence
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