Recombinant human CD69 protein
CD69, also known as early activation antigen CD69, is a type 2 transmembrane glycoprotein in the C-type lectin family. Also, CD69 is a very early activation Ag of T lymphocytes. It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. This protein plays a role in the pathogenesis of allergen induced eosinophilic airway inflammation and responsiveness. Recombinant human CD69, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
17 kDa (147aa)
Additionnal Information
References & Citations
Li J., et al. (2013) Cell. Immunol. 285:23-30.; ; Gonzalez-Amaro R., et al. (2013) Trends Mol. Med. 19 (10) :625-632.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001772
Uniprot Accession Number
Q07108
Species
Human
N Terminal Sequence
Ala
AA Sequence
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