Recombinant human FLRT2 protein

FLRT2, also known as leucine-rich repeat transmembrane protein FLRT2, is one of three FLRT (fibronectin, leucine rich repeat, transmembrane) glycoproteins expressed in distinct areas of the developing brain and other tissues. Human FLRT1 and FLRT3 ECDs (extracellular domain) share approximately 47% aa identity with FLRT2. The fibronectin domain of all three FLRTs can bind to FGF receptors. Recombinant human FLRT2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

FLRT2

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

57.5 kDa (514aa)

Additionnal Information

FLRT2, FLRT2, ATGP3291-10 µg, ATGP3291-20 µg, ATGP3291-50 µg, ATGP3291-100 µg, ATGP3291-250 µg, ATGP3291-500 µg, ATGP3291-1 mg, ATGP3291-10, ATGP3291-20, ATGP3291-50, ATGP3291-100, ATGP3291-250, ATGP3291-500, ATGP3291-1

References & Citations

Haines B.P., et al. (2006) Dev. Biol. 297:14-25.; ; Lacy S.E., et al. (1999) Genomics. 62:417-426.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_037363

Uniprot Accession Number

O43155

Species

Human

AA Sequence

CPSVCRCDRN FVYCNERSLT SVPLGIPEGV TVLYLHNNQI NNAGFPAELH NVQSVHTVYL YGNQLDEFPM NLPKNVRVLH LQENNIQTIS RAALAQLLKL EELHLDDNSI STVGVEDGAF REAISLKLLF LSKNHLSSVP VGLPVDLQEL RVDENRIAVI SDMAFQNLTS LERLIVDGNL LTNKGIAEGT FSHLTKLKEF SIVRNSLSHP PPDLPGTHLI RLYLQDNQIN HIPLTAFSNL RKLERLDISN NQLRMLTQGV FDNLSNLKQL TARNNPWFCD CSIKWVTEWL KYIPSSLNVR GFMCQGPEQV RGMAVRELNM NLLSCPTTTP GLPLFTPAPS TASPTTQPPT LSIPNPSRSY TPPTPTTSKL PTIPDWDGRE RVTPPISERI QLSIHFVNDT SIQVSWLSLF TVMAYKLTWV KMGHSLVGGI VQERIVSGEK QHLSLVNLEP RSTYRICLVP LDAFNYRAVE DTICSEATTH ASYLNNGSNT ASSHEQTTSH SMGSPFLEHH HHHH