Recombinant mouse CD5L protein
CD5L, also known as CD5 antigen-like, plays a role in the regulation of the immune system. CD5L which is a secreted glycoprotein and expressed by macrophages presenting lymphoid tissues such as bone marrow, lymph node and thymus is up-regulated in macrophage at inflammatory sites. It sustains inflammatory reactions by both increasing the phagocytic capacity of macrophage and impeding the apoptosis of local macrophages, NK cells and T cells. Recombinant mouse CD5L, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Cd5l, Apoptosis inhibitory 6, CT-2, SP-alpha, AAC-11
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
37.6 kDa (339aa)
Additionnal Information
References & Citations
Martinez VG et al., (2014) Cell Mol. Immunol. 11 (4) :343-54.; ; Sarrias MR et al., (2005) J. Biol. Chem. 280 (42) :35391-35398.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Apoptosis
NCBI Accession Number
AAH94459
Uniprot Accession Number
Q9QWK4
Species
Mouse
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