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Recombinant mouse TrkB protein

NTRK2, also known as BDNF/NT-3 growth factors receptor, is a member of the neurotrophic tyrosine receptor kinase family. This protein involves in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, differentiation, and synapse formation and plasticity. Recombinant mouse NTRK2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Ntrk2, GP145-TrkB/GP95-TrkB, Tkrb, trk-B, trkB

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

45.7 kDa (409aa)

Additionnal Information

TrkB, Ntrk2, GP145-TrkB/GP95-TrkB, Tkrb, trk-B, trkB, ATGP3204-10 µg, ATGP3204-20 µg, ATGP3204-50 µg, ATGP3204-100 µg, ATGP3204-250 µg, ATGP3204-500 µg, ATGP3204-1 mg, ATGP3204-10, ATGP3204-20, ATGP3204-50, ATGP3204-100, ATGP3204-250, ATGP3204-500, ATGP3204-1

References & Citations

Heldt SA et al., (2014) J. Neurosci., 34: (7) 2444-2450.; ; Xiang J et al., (2014) J. Clin. Invest., 124: (1) 85-98.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_001020245

Uniprot Accession Number

P15209

Species

Mouse

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