Recombinant mouse Bcl-xL protein
BCL2L1 also known as Bcl-2-like protein 1 isoform a. This protein is a member of BCL-2 protein family. BCL2L1 is located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. Also, BCL2L1 controls a switch between cell death modes during mitotic arrest. Recombinant mouse BCL2L1, fused to His-tag at N-terminus was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Bcl (X) L, bcl-x, bcl-XL, bcl-L-1, bcl2l, bclX, Bcl2l1
Expression System
E.coli
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Purity
> 95% by SDS-PAGE
Molecular Weight
25.8 kDa (232aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Bah N., et al. (2014) Cell death dis. doi: 10.1038 ; ; Yang X F., et al. (1997) Immunity. 7 (5) : 629-39.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_001276645
Uniprot Accession Number
Q64373
Species
Mouse
AA Sequence
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