Recombinant mouse Decorin protein
DCN, also known as decorin, is a proteoglycan known to interact with collagen and growth factors, may play key roles during ontogenesis, tissue remodeling, and cancer. It regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors FGF-2, GDF-8/Myostatin, TGF-Beta, and WISP-1. Recombinant mouse DCN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Dcn, DC, DSPG2, mDcn, PG40, PGII, PGS2, SLRR1B
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
38.8 kDa (344aa)
Additionnal Information
References & Citations
Scholzen T. et al., (1994) J. Biol. Chem. 269:28270-28281.; ; Zamfir A. et al., (2003) Glycobiology 13: 733.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 0.1mM PMSF
Scientific Category
Cardiovascular
NCBI Accession Number
NP_001177380
Uniprot Accession Number
P28654
Species
Mouse
AA Sequence
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