Recombinant human MAGEA8 protein
MAGEA8 also known as Melanoma-associated antigen 8 is a member of the MAGE gene family, which comprises 12 known genes, of which 6 are expressed in tumors. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. Recombinant human MAGEA8, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Product Specifications
Product Name Alternative
Melanoma-associated antigen 8, CT1.8, MAGE8
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
37.6 kDa (341aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Serrano A., et al. (1999) Int. J. Cancer 83 (5), 664-669; ; Rogner uC., et al. (1995) Genomics 29 (3), 725-731;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_001159873
Uniprot Accession Number
P43361
Species
Human
AA Sequence
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