Recombinant human SUOX protein
SuOX also known as sulfite oxidase. SuOX is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. This enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. SuOX deficiency results in neurological abnormalities which are often fatal at an early age. Recombinant human SuOX protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Sulfite oxidase
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
53.9 kDa (489aa)
Additionnal Information
References & Citations
Rudolph M.J., et al. (2003) Acta Crystallogr. D 59:1183-1191.; ; Kisker C., et al. (1997) Cell 91:973-983.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT
Scientific Category
Metabolism
NCBI Accession Number
NP_000447.2
Uniprot Accession Number
P51687
Species
Human
AA Sequence
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