Recombinant human Wnt-3a protein
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT3a is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This protein is clustered with WNT14 gene, another family member, in chromosome 1q42 region. Recombinant human WNT3a protein was expressed in E. coli.
Product Specifications
Product Name Alternative
Wnt3a, Wingless-type MMTV integration site family, member 3A
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
37.5 kDa (335aa)
Additionnal Information
References & Citations
Baenziger C., et al. (2006) . Cell 125:509-522; ; Bourhis E., et al. (2010) . J. Biol. Chem. 285:9172-9179;
Other References
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_149122.1
Uniprot Accession Number
P56704
Species
Human
AA Sequence
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