Recombinant human COMMD6 protein
COMMD6 contains 1 COMM domain. This protein down-regulates activation of NF-kappa-B and inhibits TNF-induced NFKB1 activation. Recombinant human COMMD6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
COMM domain-containing protein 6 isoform b, Acrg
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
12.0 kDa (108aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
De Bie P. et al. (2006) Biochem J. 398 :63-71; ; Burstein E. et al. (2005) J Biol Chem. 280:22222-22232.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH7.0) containing 20% glycerol 0.15M NaCl, 1mM DTT
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_987091.1
Uniprot Accession Number
Q7Z4G1
Species
Human
AA Sequence
MEASSEP PLDAKSDVTN QLVDFQWKLG MAVSSDTCRS LKYPYVAVML KVADHSGQVK TKCFEMTIPQ FQNFYRQFKE IAAVIETV
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