Recombinant human UGT8 protein
UDP glycosyltransferase 8, also known as uGT8, catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Recombinant human uGT8 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
61.6 kDa (544aa)
Additionnal Information
References & Citations
Bosio A., et al. (1996) Genomics. 34:69-75; ; Kapitonov D.E., et al. (1997) Biochem. Biophys. Res. Commun. 232:449-453;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Metabolism
NCBI Accession Number
NP_003351
Uniprot Accession Number
Q16880
Species
Human
AA Sequence
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