Recombinant human TCEA2 protein
TCEA2 is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human TCEA2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Transcription elongation factor A protein 2 isoform a, transcription elongation factor A (SII), 2, TFIIS
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
36 kDa (322aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Weaver ZA, Kane CM. Mar 1998. Genomics 46 (3) : 516-9.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.25M NaCl
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_003186
Uniprot Accession Number
Q15560
Species
Human
AA Sequence
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