Recombinant human TOR1A protein
TOR1A is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1. Recombinant human TOR1A protein, His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Torsin-1A, DQ2, DYT1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
38 kDa (333aa)
Additionnal Information
References & Citations
Schmidt A, et al. (2012) . Parkinsonism Relat Disord. 2012 Jun; ;18 (5) :690-1.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
AAH00674
Uniprot Accession Number
O14656
Species
Human
AA Sequence
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