Recombinant human OMP protein
Olfactory marker protein, also known as OMP, is uniquely associated with the mature olfactory receptor neurons in many vertebrate species from fish to man. It is expressed in the cytoplasm of olfactory chemosensory neurons in the nasal neuroepithelium. OMP expression is a sign of mature vertebrate olfactory receptor neurons (ORNs) . OMP may have a modulatory role in the odor detection/signal transduction cascade. In fetal olfactory epithelial cells, OMP is also a potent enhancer of mitosis, and it promotes an increase in uptake of tritiated thymidine in liver. Recombinant human OMP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Olfactory marker protein, Olfactory marker protein, olfactory neuronal-specific protein
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by BCA assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
21.3 kDa (186aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Buiakova O I., et al. (1996) Proc Natl Acad Sci uSA. 93:9858-9863; ; Behrens M., et al. (2003) J Neurochem. 86: 1289-1296.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Neuroscience
NCBI Accession Number
NP_006180
Uniprot Accession Number
P47874
Species
Human
AA Sequence
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