Recombinant human EpCAM/TROP-1 protein
Epithelial cell adhesion molecules, also known as EPCAM, may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. This protein plays a role in embryonic stem cells proliferation and differentiation. Recombinant human EPCAM protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Epithelial cell adhesion molecules, CD326, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1, DIAR5, EGP, GA733 2, HNPCC8
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
30.1 kDa (267aa)
Additionnal Information
References & Citations
Muenz M., et al. (2004) Oncogene.23:5748-5758; ; Muenz M., et al. (2005) Cancer Lett. 225:151-157;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_002345
Uniprot Accession Number
P16422
Species
Human
AA Sequence
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