Recombinant human TRAPPC2 protein
TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, this protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in TRAPPC2 are a cause of spondyloepiphyseal dysplasia tarda (SEDT) . Recombinant human TRAPPC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
ZNF547L, TRS20, TRAPPC2P1, Trafficking protein particle complex subunit 2, Spondyloepiphyseal dysplasia late, SEDT, Sedlin, SEDL, MIP2A, hYP38334
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
18.8 kDa (163aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Gecz J, Shaw MA, et al. (2003) . Gene. 27; ;320:137-44.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_055378
Uniprot Accession Number
P0DI81
Species
Human
AA Sequence
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