Recombinant human DYNLT1 protein

Dynein light chain Tctex-type 1, also known as DYNLT1, belongs to the dynein light chain Tctex-type family. DYNLT1 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. DYNLT1 is a dynein light chain involved in cargo binding. Recombinant human DYNLT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.