Recombinant human CABP7 protein

CABP7, also known as Calcium-binding protein 7, contains two EF-hand domains. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. The CaBP family of EF-hand containing small Ca (2+) -binding proteins has recently emerged as important regulators of multiple targets essential to normal neuronal function in the mammalian central nervous system. Recombinant human CABP7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Calcium-binding protein 7, Calneuron II, Calneuron-2, CALN2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

23.7 kDa (208aa) confirmed by MALDI-TOF

Additionnal Information

CABP7, Calcium-binding protein 7, Calneuron II, Calneuron-2, CALN2, ATGP1031-10 µg, ATGP1031-20 µg, ATGP1031-50 µg, ATGP1031-100 µg, ATGP1031-250 µg, ATGP1031-500 µg, ATGP1031-1 mg, ATGP1031-10, ATGP1031-20, ATGP1031-50, ATGP1031-100, ATGP1031-250, ATGP1031-500, ATGP1031-1

References & Citations

McCue H.V., et al. (2009) Biochem. Biophys. Res. Commun. 380:825-831; ; Yu L. R., et al. (2007) J. Proteome Res. 6:4150-4162

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-buffered saline (pH 7.4)

Scientific Category

Signal Transduction

NCBI Accession Number

NP_872333

Uniprot Accession Number

Q86V35

Species

Human

AA Sequence

MPFHPVTAAL MYRGIYTVPN LLSEQRPVDI PEDELEEIRE AFKVFDRDGN GFISKQELGT AMRSLGYMPN EVELEVIIQR LDMDGDGQVD FEEFVTLLGP KLSTSGIPEK FHGTDFDTVF WKCDMQKLTV DELKRLLYDT FCEHLSMKDI ENIIMTEEES HLGTAEECPV DVETCSNQQI RQTCVRKS