Recombinant human DYNLRB2 protein
DYNLRB2, also known as dynein light chain roadblock-type 2, acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Recombinant human DYNLRB2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Dynein light chain roadblock-type 2, DNCL2B, DNLC2B, MGC62033, ROBLD2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
13.0 kDa (116aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Jiang J., et al. (2001) . Gene., 281:103-13.; ; Wanschers B., et al. (2008) . Cell Motil Cytoskeleton. 65:183-96.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Scientific Category
Adhesion & Movement
NCBI Accession Number
NP_570967
Uniprot Accession Number
Q8TF09
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MAEVEETLKR IQSHKGVIGT MVVNAEGIPI RTTLDNSTTV QYAGLLHHLT MKAKSTVRDI DPQNDLTFLR IRSKKHEIMV APDKEYLLIV IQNPCE
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