Recombinant human MESDC2 protein

MESDC2, also known as Mesoderm development candidate 2, is required for formation of the primitive streak and mesoderm during embryogenesis. This protein binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression. Recombinant human MESDC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

LDLR chaperone MESD, BOCA, KIAA0081, MESD

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by BCA assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

24.9 kDa (222aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

MESDC2, LDLR chaperone MESD, BOCA, KIAA0081, MESD, ATGP0933-10 µg, ATGP0933-20 µg, ATGP0933-50 µg, ATGP0933-100 µg, ATGP0933-250 µg, ATGP0933-500 µg, ATGP0933-1 mg, ATGP0933-10, ATGP0933-20, ATGP0933-50, ATGP0933-100, ATGP0933-250, ATGP0933-500, ATGP0933-1

References & Citations

Kohler C, et al. (2006) . J Struct Funct Genomics, 7:131-8.; ; Wines ME., et al. (2001) . Genomics., 72:88-98.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% Glycerol

Scientific Category

Heat Shock Proteins

NCBI Accession Number

NP_055969

Uniprot Accession Number

Q14696

Species

Human

AA Sequence

AEGSPGTPD ESTPPPRKKK KDIRDYNDAD MARLLEQWEK DDDIEEGDLP EHKRPSAPVD FSKIDPSKPE SILKMTKKGK TLMMFVTVSG SPTEKETEEI TSLWQGSLFN ANYDVQRFIV GSDRAIFMLR DGSYAWEIKD FLVGQDRCAD VTLEGQVYPG KGGGSKEKNK TKQDKGKKKK EGDLKSRSSK EENRAGNKRE DL