Recombinant human CAPS protein
Calcyphosine, also known as CAPS, is a calcium-binding protein containing four EF-hand domains. CAPS is initially identified as thyroid protein p24 that is found in several epithelium and in some cells of the central nervous system. It may play a role in the regulation of ion transport. In thyroid follicular cells, CAPS is synthesized and phosphorylated in response to stimulation by thyrotropin and cAMP agonists. Recombinant human CAPS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Calcyphosine, CAPS1, Calcyphosin
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
23.1 kDa (209aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
El Housni H, et al. (1997) Mol Cell Endocrinol. 135 (1) :93-7.; ; Halleux P, et al. (1998) J Chem Neuroanat. 15 (4) :239-50.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 100 mM NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_004049
Uniprot Accession Number
K7EL21
Species
Human
AA Sequence
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