Recombinant human DNAJC19 protein

DNAJC19 is a single-pass membrane protein that contains a J domain and is localized to the inner membrane of the mitochondrion. Expressed ubiquitously, DNAJC19 functions as a component of the mitochondrial DNAJC19 complex, which is responsible for the ATP-dependent translocation of select proteins from the inner mitochondrial membrane to the mitochondrial matrix. Defects in DNAJC19 are the cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA) . Recombinant human DNAJC19 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Mitochondrial import inner membrane translocase subunit TIM14, Pam18, TIM14, TIMM14

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

15.1 kDa (135aa) confirmed by MALDI-TOF

Additionnal Information

TIMM-14, TIMM14, TIMM 14, TIM-14, TIM14, TIM 14, Pam-18, Pam18, Pam 18, Mitochondrial import inner membrane translocase subunit TIM-14, Mitochondrial import inner membrane translocase subunit TIM14, Mitochondrial import inner membrane translocase subunit TIM 14, DNAJC19, ATGP0911-10 µg, ATGP0911-20 µg, ATGP0911-50 µg, ATGP0911-100 µg, ATGP0911-250 µg, ATGP0911-500 µg, ATGP0911-1 mg, ATGP0911-010, ATGP0911-020, ATGP0911-050, ATGP0911-100, ATGP0911-250, ATGP0911-500, ATGP0911-01M