Recombinant human IGF-2 protein
IGF2, as known as insulin-like growth factor 2, is mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. This protein is a fetal growth factor, influenced by placental lactogen and abundantly expressed by placental trophoblasts. Recombinant human IGF2 was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Product Specifications
Product Name Alternative
Insulin-like growth factor 2, Somatomedin-A, INSIGF, Preptin, Insulin-like growth factor II, IGF-II, T3M-11-derived growth factor
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
7.6 kDa (68aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Bell G.I., et al. (1984), Nature 310: 775-777; ; Pedersen S.K., et al. (2002) . Biochem. J. 363: 37-44.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. phosphate-buffered saline (pH 7.4) containing 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_000603
Uniprot Accession Number
P01344
Species
Human
AA Sequence
MAYRPSETLC GGELVDTLQF VCGDRGFYFS RPASRVSRRS RGIVEECCFR SCDLALLETY CATPAKSE
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