Recombinant E.coli secB protein
SecB, a remarkable chaperone involved in protein export, binds diverse ligands rapidly with high affinity and low specificity. It plays a crucial role during protein export via the general secretory pathway by modulating the partitioning of precursors between folding or aggregation and delivery to the membrane-bound translocation apparatus. SecB has the potential to participate in functions outside of export acting as a general nonspecific chaperone to provide buffering capacity of the nonnative state of proteins in the cytosolic pool. Recombinant E. coli SecB protein was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Protein export chaperone, SecB, Protein export protein secB, Chaperone SecB
Expression System
E.coli
Antigen Species
E.coli
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Absorbance at 280 nm)
Purity
> 95% by SDS-PAGE
Molecular Weight
17.2 kDa (155aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Driessen AJ., et al. (2008), Annu Rev Biochem. 77:643-67.; ; Bechtluft P., et al. (2007) . Science. 318 (5855) :1458-61.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_418066
Uniprot Accession Number
P0AG86
Species
E.coli
AA Sequence
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