FSBP cDNA

Fibrinogen silencer-binding protein, also known as FSBP, is interacts with X11alpha. X11alpha/FSBP complex signals to the nucleus to repress glycogen synthase kinase-3beta promoter activity. X11alpha is a neuronal adaptor protein that interacts with the amyloid precursor protein (APP) through a centrally located phosphotyrosine binding domain to inhibit the production of Abeta peptide that is deposited in Alzheimer's disease brains.

Product Specifications

Chromosomal Location

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGGTAGGAAAGGCTAGATCTTCCAATTTTACCTTATCCGAAAAGCTTGATTTGCTAAAGCTTGTGAAGCCATATGTGAAAATTCTCGAAGAACACACTAATAAACATTCAGTAATAGTAGAAAAGAATAGATGTTGGGATATCATAGCAGTTAACTATAATGCAATTGGAGTAGACCGCCCTCCTCGAACAGCACAGGGCCTACGCACCCTTTATAAAAGGCTCAAAGAATATGCCAAACAGGAGCTATTGCAGCAAAAAGAGACCCAATCAGATTTTAAAAGCAATATTTCTGAGCCAACCAAGAAAGTTATGGAGATGATTCCCCAGATTTCCAGTTTTTGCCTGGTAAGAGACAGGAACCACATACAAAGTGCAAACTTGGATGAGGAGGCACAGGCTGGTACCAGTTCACTACAGGTAATGTTGGATCACCATCCTGTTGCTATTACAGTGGAGGTGAAGCAAGAAGAAGACATTAAACCACCTCCTCCACTGGTTTTAAATTCTCAACAGAGTGATACTTTAGAGCAAAGAGAAGAACATGAATTAGTACATGTTATGGAAAGATCCTTGTCGCCTTCACTTTCCTCTGTTGATATGAGAATGACATCGTCTCCATCTTCTATTCCAAGGAGAGATGATTTTTTTCGGCATGAGAGTGGTGAACACTTTAGGTCACTATTAGGGTATGATCCTCAGATCCTGCAAATGTTGAAAGAGGAGCATCAGATAATTTTAGAAAATCAAAAAAATTTTGGATTGTATGTTCAGGAGAAGAGGGATGGATTGAAAAGAAGGCAGCAGCTAGAGGAAGAGCTACTAAGAGCAAAAATTGAAGTGGAGAAGCTGAAAGCAATTCGCTTACGGCATGATCTACCTGAATATAACAGTCTCTAA

Additionnal Information

FSBP, FSBP, ATGD0494-10 µg, ATGD0494-20 µg, ATGD0494-50 µg, ATGD0494-100 µg, ATGD0494-250 µg, ATGD0494-500 µg, ATGD0494-1 mg, ATGD0494-10, ATGD0494-20, ATGD0494-50, ATGD0494-100, ATGD0494-250, ATGD0494-500, ATGD0494-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Cancer

Omim

616306

NCBI Accession Number

NP_001243070.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_001256141.1

DNA Size

900bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.