Galaxolide

Galaxolide can induce estrogenic activity (Estrogen Receptor/ERR), trigger oxidative stress and genotoxicity, and induce EROD and GST (Glutathione S-transferase) enzyme activity[1][2].

Product Specifications

CAS Number

[1222-05-5]

UNSPSC

12352005

Hazard Statement

H410

Target

Estrogen Receptor/ERR; Glutathione S-transferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/galaxolide.html

Concentration

10mM

Purity

76.44

Smiles

CC1COCC2=CC3=C(C=C12)C(C)(C)C(C)C3(C)C

Molecular Formula

C18H26O

Molecular Weight

258.40

Precautions

H410

References & Citations

[1]Jo-Anne E Cavanagh, et al. Assessment of endocrine disruption and oxidative potential of bisphenol-A, triclosan, nonylphenol, diethylhexyl phthalate, galaxolide, and carbamazepine, common contaminants of municipal biosolids. Toxicol In Vitro. 2018 Apr:48:342-349.|[2]Friday O Ehiguese, et al. Potential of environmental concentrations of the musks galaxolide and tonalide to induce oxidative stress and genotoxicity in the marine environment. Mar Environ Res. 2020 Sep:160:105019.