Propargyl-PEG8-NHS ester
Product Specifications
UNSPSC Description
Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG8-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/propargyl-peg7-c2-nhs-ester.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
C#CCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
Molecular Weight
533.57
References & Citations
[1]Satwik Kamtekar, et al. Modified biotin-binding proteins for immobilization. WO2019126734A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130376/Propargyl-PEG8-NHS-ester-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130376/Propargyl-PEG8-NHS-ester-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2182601-74-5
Available Sizes
Curated Selection
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