Rb Polyclonal Antibody

Product Specifications

Background

RB transcriptional corepressor 1 (RB1) Homo sapiens The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]

Product Name Alternative

RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110

Gene ID

5925

Swiss Prot

P06400

Cross Reactivity

Human; Mouse; Rat

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC-p; IF/ICC; ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.