P53 mouse mAb (PT0337)
Product Specifications
Background
Tumor protein p53 (TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277) . [provided by RefSeq, Feb 2013]
Product Name Alternative
Cellular tumor antigen p53 (Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53)
Gene ID
7157
Swiss Prot
P04637
Cross Reactivity
Human
Clonality
Monoclonal
Source
Mouse
Applications
IHC-p; IF (paraffin section) ; WB
Dilution
IHC-p 1:100-300, WB 1:500-2000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Conditions
-20°C/1 year
Available Sizes
Curated Selection
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