HDAC3 mouse mAb
Product Specifications
Background
Histone deacetylase 3 (HDAC3) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
Product Name Alternative
HD 3; HD3; HDAC 3; HDAC3; HDAC3_HUMAN; Histone deacetylase 3 (HD3) (RPD3-2) ; histone deacetylase 3; RPD 3; RPD3 2; RPD3; RPD3-2; SMAP 45; SMAP45.
Gene ID
8841
Swiss Prot
O15379
Cross Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Source
Mouse
Applications
WB
Dilution
Wb 1:1000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
49
Storage Conditions
-20°C/1 year
Protein Weight
49
Available Sizes
Curated Selection
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