E2F-1 mouse mAb

E2F transcription factor 1 (E2F1) Homo sapiens The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media

Dmel\CG6376 ; Dmel_CG6376 ; drosE2F1 ; E (Sev-CycE) 3A ; E (var) 3-93E ; E2-promoter binding facto ; E2F 1 ; E2F transcription factor 1 ; E2F-1 ; E2f-PA ; E2f-PB ; E2f-PC ; E2F1 ; E2f1 E2F transcription factor 1 ; E2F1_HUMAN ; Evar (3) 164 ; KIAA4009 ; l (3) 07172 ; l (3) j3B1 ; l (3) j3C2 ; l (3) rM729 ; mKIAA4009 ; OTTHUMP00000030661 ; PBR3 ; PRB binding protein E2F 1 ; PRB-binding protein E2F-1 ; RBAP 1 ; RBAP-1 ; RBAP1 ; RBBP-3 ; RBBP3 ; RBP 3 ; RBP3 ; Retinoblastoma-associated protein 1 ; Retinoblastoma-binding protein 3 ; Transcription factor E2F1.