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BACE Monoclonal Antibody

Product Specifications

Background

Beta-secretase 1 (BACE1) Homo sapiens This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015]

Product Name Alternative

BACE1; BACE; KIAA1149; Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2

Gene ID

23621

Swiss Prot

P56817

Cross Reactivity

Human; Rat; Bovine; Dog; Pig

Clonality

Monoclonal

Source

Mouse

Applications

WB

Dilution

Western Blot: 1/1000 - 1/2000. Not yet tested in other applications.

Buffer

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage Conditions

-20°C/1 year

Available Sizes

Curated Selection

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