KRAS, Human (G12V, His)
Product Specifications
UNSPSC Description
KRAS protein is a key Ras family member that binds GDP/GTP and has intrinsic GTPase activity. Its critical role in regulating cell proliferation emphasizes its importance in cellular processes. KRAS Protein, Human (G12V, His) is the recombinant human-derived KRAS protein, expressed by E. coli , with N-6*His labeled tag and G12V, , , , mutation. The total length of KRAS Protein, Human (G12V, His) is 184 a.a., with molecular weight of 25-30 kDa, observed by reducing SDS-PAGE.
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/kras-protein-human-g12v-his.html
Purity
95.00
Smiles
HHHHHHTEYK LVVVGAVGVG KSALTIQLIQ NHFVDEYDPT IEDSYRKQVV IDGETCLLDI LDTAGHEEYS AMRDQYMRTG EGFLCVFAIN NTKSFEDIHH YREQIKRVKD SEDVPMVLVG NKCDLPSRTV DTKQAQDLAR SYGIPFIETS AKTRQGVDDA FYTLVREIRK HKEKMSKDGK KKKKKSKTKC
Molecular Weight
25-30 kDa, observed by reducing SDS-PAGE
References & Citations
[1]Jianhua Ling, et al. KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell. 2012 Jan 17;21(1):105-20.
Shipping Conditions
Blue Ice
Storage Conditions
Stored at -20°C for 2 years
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
