Calbindin Antibody

Product Specifications

Background

Calbindin (aka. calbindin D28k) is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. It is predominantly expressed in certain types of neurons, particularly in dendrites and perikarya of the cerebellum and is thought to buffer entry of calcium upon stimulation of glutamate receptors (Andressen et al., 1993) . Calbindin has recently been shown to play a critical role in mitochondrial dysfunction and loss of synaptic proteins in vivo in an Alzheimer’s disease mouse model (Kook et al., 2014) .

Synonyms

Avian-type antibody, CAB27 antibody, CALB 1 antibody, CALB antibody, CALB1 antibody, CALB1_HUMAN antibody, Calbindin 1 28kDa antibody, Calbindin antibody, Calbindin D28 antibody, D 28K antibody, D-28K antibody, D28K antibody, OTTHUMP00000166027 antibody, OTTHUMP00000225441 antibody, RTVL H protein antibody, Vitamin D dependent calcium binding protein antibody, Vitamin D dependent calcium binding protein avian type antibody, Vitamin D-dependent calcium-binding protein antibody

Gene ID

793

Swiss Prot

P05937

Host

Mouse

Cross Reactivity

Human, Mouse, Rat, Bovine

Target

Calbindin

Clonality

Monoclonal

Isotype

IgG2a

Clone

5A9

Conjugation

Unconjugated

Source

Recombinant full length human calbindin purified from E. coli.

Applications

WB, IHC

Purification

Purified by Protein G.

Concentration

Lot Dependent

Dilution

WB (1:300-5000), IHC ()

Buffer

PBS + 50% glycerol and 5 mM NaN3

Modification

Unmodified

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.