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TRAP1/HSP75 Recombinant Antibody

Product Specifications

Background

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Synonyms

HSP75; HSP 75; HSP90L; TRAP-1.

Gene ID

10131

Swiss Prot

Q12931

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

TRAP1/HSP75

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human Hsp75

Applications

WB, IP

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IP (1-2ug)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

10131

Available Sizes

Curated Selection

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