RAB7L1 Monoclonal Antibody
Product Specifications
Background
Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS) . May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection.
Synonyms
RAB29; DKFZp686P1051; Rab 7 like protein 1; RAB 7L; Rab7 like protein 1; RAB7 member RAS oncogene family like 1; RAB7L; Ras related protein Rab 7L1; Ras-related protein Rab-7L1; Ras related protein Rab7L1.
Gene ID
8934
Swiss Prot
O14966
Cellular Locus
Cytoplasm, Cell membrane
Host
Mouse
Cross Reactivity
Human
Target
RAB7L1
Clonality
Monoclonal
Isotype
IgG1
Clone
L6G11
Conjugation
Unconjugated
Source
Recombinant human RAB7L1.
Applications
WB
Concentration
0.5µg/µl
Dilution
WB (WB=1:500-2000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Product Datasheet
https://www.biossantibodies.com/datasheets/bsm-51688M
Gene ID URL
8934
Curated Selection
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