AFAP Polyclonal Antibody
Product Specifications
Background
Can cross-link actin filaments into both network and bundle structures (By similarity) . May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
Synonyms
AFAP; AFAP110; AFAP-110; Actin filament-associated protein 1; 110 kDa actin filament-associated protein; AFAP1
Gene ID
60312
Swiss Prot
Q8N556
Host
Rabbit
Cross Reactivity
Human
Immunogen
277-345/730
Target
AFAP
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human AFAP
Applications
WB, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
60312
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Sheep, Horse
Curated Selection
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