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PI14 Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

SERPINI2 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

Synonyms

MEPI; Myoepithelium derived serine protease inhibitor; Pancpin; Pancreas specic protein TSA2004; Peptidase inhibitor 14; PI 14; PI14; Protease inhibitor 14; Serine or cysteine proteinase inhibitor clade I neuroserpin member 2; Serine or cysteine proteinase inhibitor clade I pancpin member 2; Serpin I2; Serpin peptidase inhibitor clade I pancpin member 2; TSA2004; SPI2_HUMAN; SERPINI2.

Gene ID

5276

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

151-250/405

Target

PI14

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human SERPINI2/PI14

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5276

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