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PHF8 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe (2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD) . Four transcript variants encoding different isoforms have been found for this gene.

Synonyms

PHD finger protein 8; PHD finger protein 8; Histone lysine demethylase PHF8; PHD finger protein 8; PHF8; PHF8_HUMAN; ZNF422.

Gene ID

23133

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

501-600/1060

Target

PHF8

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human PHF8

Applications

ELISA, FCM

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), FCM (1:20-100)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

23133

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit

Curated Selection

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